This is the story of Setsuko Nakamura Thurlow—a teenage girl living in Hiroshima in 1945, when the city was annihilated by an atomic bomb. Struggling with grief and anger, Thurlow set out to warn the world about the horrors of a nuclear attack in a crusade that has lasted decades. In 2015 Thurlow sparked a rallying cry for activists when she proclaimed at the United Nations, "Humanity and nuclear weapons cannot coexist." With that, she shifted the global discussion from nuclear deterrence to humanitarian consequences, the key in crafting the landmark Treaty on the Prohibition of Nuclear Weapons. Regarded as the conscience of the antinuclear movement, Thurlow accepted the 2017 Nobel Peace Prize on behalf of the International Campaign to Abolish Nuclear Weapons. In 2021, the Treaty on the Prohibition of Nuclear Weapons went into effect, banning nuclear weapons under international law.

Critical historical events need a personal narrative, and Thurlow is such a storyteller for Hiroshima. 90 Seconds to Midnight recounts Thurlow's ascent from the netherworld where she saw, heard, and smelled death and her relentless efforts to protect the world from an unspeakable fate. Knowing she would have to live with those nightmares, Thurlow turned them into a force to impel people to learn from Hiroshima, to admit that yes, it could happen again—and then to take action.