The Resident Patient: When a father and son disappear, Holmes is called in to find out why the doctor's benefactor is now the most frightened man in town.

The Greek Interpreter: In this adventure we are introduced to Holmes' brother Mycroft, the only relative of whom Watson's friend openly spoken during their long assocation. Mycroft, says Holmes, is Sherlock's superior but cannot put the gifts to use. They stroll to the singular accomodations of the Diogenes Club, and as Watson becomes acquainted with the elder Holmes, Mycroft introduces them to a Grecian interpreter. The man's story draws the detective and his companion into a case of extortion and violence.

The Naval Treaty: Holmes must recover a document, prevent a crisis between England and Italy, and save the career of a rising diplomat.

The Final Problem: Sherlock Holmes' determination to destroy the criminal organization of Professor Moriarty reaches its crisis as Holmes and Watson attempt to track down and apprehend its Master.

The Adventure of the Empty House: While grieving over his great friend's death, Watson is stunned when Holmes suddenly appears and reveals that he has escaped an untimely end in that fatal struggle with his mortal enemy, Moriarty, at Reichenbach Falls. The underworld suspects this, says Holmes, and Watson is drawn into Holmes's plot to deceive his enemies and foil an attempt upon his life.

The Adventure of the Norwood Builder: Young McFarland is accused of the murder of a man who has just left all his goods to the accused in his will. The evidence against the detective's client mounts and Holmes admits to Watson that, perhaps, Lestrade's case is as sound as Holmes believes it is untrue.