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Tras la desaparición de su padre, Mary Morstan recibe una extraña carta de alguien que le podría informar sobre el paradero del mismo. El desconocido remitente quiere reunirse con Mary, por lo que la joven acude a Sherlock Holmes, especialista en asuntos extraños. El desconocido resulta ser Thaddeus Sholto, hijo de un buen amigo del padre de Mary. Thaddeus contactó con Mary porque ha encontrado un tesoro en la casa familia; ahora todo lo que tienen que hacer es ir allí y dividirlo.

El detective Sherlock Holmes es un genio de la observación, la deducción lógica y la ciencia forense. Posee un profundo conocimiento de la química y, sobre todo, un sentido común único. Cualquier detalle que parece indiferente, cobra ante sus ojos pleno sentido. Y así, de detalle en detalle, Holmes va encontrando a los culpables de los crímenes que analiza.

Holmes recibe un mensaje de Porlock, uno de los agentes del profesor Moriarty. A pesar de que la ley ve a Moriarty como inocente, el detective cree firmemente que es artífice y señor de todo un inframundo criminal. Sherlock, ayudado por Watson, descifra el mensaje de Porlock y descubren que la vida de John Douglas, que reside en Birlstone, está en peligro. Poco después, Scotland Yard informa a Sherlock y Watson que el Sr. Douglas fue encontrado asesinado.

La historia comienza con el Dr. John Watson, que se instala en Londres para recuperarse de una herida que sufrió mientras actuaba como médico militar durante la Segunda Guerra de Afganistán. Por una serie de casualidades del destino, Watson conoce al excéntrico detective Sherlock Holmes. Ambos acabarán viviendo juntos, resolviendo un caso de asesinato y formando una de las parejas más reconocidas de la literatura.

Tras una majestuosa boda, la novia desaparece durante la recepción. El adinerado Lord Simon, su nuevo esposo, no tiene la más mínima idea si su nueva esposa se encuentra viva, secuestrada o si a escapado con otro hombre a sus espaldas. La ansiedad y los nervios de perderla influirán para que Simon, desesperadamente y con el corazón en la mano, solicite la ayuda de Sherlock Holmes y su fiel compañero Watson. Se supone que una boda es un momento sumamente importante de la vida. ¿Qué habrá salido mal? ¿Qué afectó en la ceremonia para que la novia desapareciera?

A Study in Scarlet is an 1887 detective novel by Scottish author Arthur Conan Doyle. The story marks the first appearance of Sherlock Holmes and Dr. Watson, who would become the most famous detective duo in popular fiction. The book's title derives from a speech given by Holmes, a consulting detective, to his friend and chronicler Watson on the nature of his work, in which he describes the story's murder investigation as his "study in scarlet": "There's the scarlet thread of murder running through the colourless skein of life, and our duty is to unravel it, and isolate it, and expose every inch of it.

A Study in Scarlet is an 1887 detective novel by Scottish author Arthur Conan Doyle. The story marks the first appearance of Sherlock Holmes and Dr. Watson, who would become the most famous detective duo in popular fiction. The book's title derives from a speech given by Holmes, a consulting detective, to his friend and chronicler Watson on the nature of his work, in which he describes the story's murder investigation as his "study in scarlet".

"A Study in Scarlet" is an 1887 detective novel by Scottish author Arthur Conan Doyle. The story marks the first appearance of Sherlock Holmes and Dr. Watson, who would become the most famous detective duo in popular fiction. The book's title derives from a speech given by Holmes, a consulting detective, to his friend and chronicler Watson on the nature of his work, in which he describes the story's murder investigation as his "study in scarlet".

In the first of all the Sherlock Holmes stories, Dr. John Watson, discharged from military service after suffering severe wounds, is at a loose end until a chance encounter leads him to take rooms with a remarkable young man. The arrogant, irascible Sherlock Holmes is a master chemist, a talented musician, and an expert on all aspects of crime.

This book served as the world's introduction to the tales of the great Sherlock Holmes, as told by his new roommate and future chronicler, Dr. Watson. Their first case involves a murder in London, Mormons, and myriad complications.

A Study in Scarlet is an 1887 detective novel by Scottish author Sir Arthur Conan Doyle. The story marks the first appearance of Sherlock Holmes and Dr. Watson, who would become the most famous detective duo in popular fiction.

When Dr. Watson returns to London from a weekend seminar, he finds hat Sherlock Holmes has been arrested. Inspector Lestrade refers Watson to a questionable psychiatric hospital where Holmes is jailed for mental incapacity.

When Dr. Watson returns to London from a weekend seminar, he finds hat Sherlock Holmes has been arrested. Inspector Lestrade refers Watson to a questionable psychiatric hospital where Holmes is jailed for mental incapacity.